GeneSilencing相关论文
Self-assembly nanoparticles based on c(RGDfk) peptide for the delivery of siRNA targeting VEGFR2 gen
The clinical application of small interference RNA (siRNA) has been restricted by poor intracellular uptake, low serum s......
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目的探讨高压氧协同靶向水通道蛋白-4(aquaporin 4,AQP-4)的RNA干扰(RNA interference,RNAi)技术对改善脑创伤(trauma brain injury,T......
Effects of miR-219/miR-338 on microglia and astrocyte behaviors and astrocyte-oligodendrocyte precur
MiR-219 and miR-338 (miR-219/miR-338) are oligodendrocyte-specific microRNAs. The overexpression of these miRs in oligod......
目的探讨沉默叉头盒O类转录因子-3a(FoxO3a)活性是否影响人卵巢癌SKOV3细胞系肿瘤球形成能力。方法干细胞条件培养基悬浮培养法得......
目的 探讨吉西他滨对Beclinl基因沉默的人胰腺癌MiaPaCa-2细胞周期及凋亡的影响.方法 构建靶向Beclinl的siRNA,插入表达质粒,转染M......
目的观察截短型p63(ΔNp63)基因沉默对胰腺癌PANC1细胞增殖的影响。方法采用实时PCR检测23例胰腺癌及其配对癌旁正常胰腺组织ΔNp6......
目的近年来,双链RNA介导的基因沉默(RNA干扰)已在许多动植物中发现,并成为研究基因功能的强有力的工具.为确定蚊虫细胞中是否有RNA......
表观遗传调控在基因表达、DNA复制、修复和重组等重要过程中起着关键作用,表观遗传调控异常会引发多种疾病尤其是癌症。SNF5是SWI-S......
目的:观察抑制Dickkopf-1和Sclerostin表达对人成骨肉瘤细胞MG63骨代谢调节相关蛋白表达水平的影响。方法:培养MG63细胞,构建沉默Dic......